A 1966 study revealed that linoleic acid (LA), the main omega-6 fat in seed oils like soybean and sunflower, lingers in your body’s fat tissue with a half-life of ~680 days (~1.9 years). Men switching to high-LA diets saw adipose LA rise from 11% to 32% over 5 years, showing it takes years to fully reflect dietary shifts.

A 2025 analysis by Georgi Dinkov highlights that polyunsaturated fats (PUFAs), prevalent in many vegetable oils, can disrupt mitochondrial function in mammals. This disruption may impair energy production and overall cellular health.