In 2025, Ewelina Młynarska and a team from the Medical University of Lodz reviewed studies on creatine monohydrate supplementation combined with exercise for preventing type 2 diabetes. They focused on how skeletal muscle, which handles most body glucose, loses function in type 2 diabetes due to insulin resistance and sarcopenia (muscle wasting), and how creatine monohydrate—found in meat/fish or supplements—might help alongside workouts like weights or aerobics.

A 2025 meta-analysis in Frontiers in Nutrition examined multiple trials comparing ketogenic diets (very low-carb, high-fat) with standard diets in cancer patients. The ketogenic group experienced significantly reduced fat mass and visceral fat, lower blood glucose and insulin, and improvements in LDL, total cholesterol, as well as fatigue and insomnia.