Aspirin Fails to Protect Older Hearts, Increases Bleeding.

In 2025, Rory Wolfe and a team analyzed the ASPREE trial with 19,114 older adults (aged 65+ for US minorities, 70+ otherwise) without prior heart issues, dementia, or disabilities. From 2010–2017, half took daily low-dose aspirin, half got a placebo, with follow-up until 2022 for 15,668 participants. They checked for heart attacks, strokes, and bleeding events.

Aspirin didn’t lower heart risks (no change in events) and raised cardiovascular event rates post-trial by 17%. It also increased major bleeding by 24% throughout, showing harm outweighs benefits for healthy seniors.

Avoid daily aspirin for heart prevention unless you have known heart disease—talk to your doctor first.